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Form 8-E UNITED STATES SECURITIES AND EXCHANGE COMMISSION Wa, D.C. 20549 FORM 8-E CURRENT Record Pursuant to Area 13 or 15(d) of the Securities Exchange Take action of 1934 Time of Review (Time of earliest event reported): April 24, 2012 Individual GENOME SCIENCES, INC. Human being GENOME SCIENCES, INC.

By: /s/ J AMES H. Chemical AVIS, G H.D.

Title: James H. Title: Executive Vice President, General Counsel and Secretary Day: April 24, 2012 Catalog TO EXHIBITS Exhibit No. Explanation 99.1 Press Release, went out with Apr 24, 2012. 99.2 Slide Display related to earnings conference contact. Former mate-99.1 2 d339062dex991.htm EX-99.1 Ex girlfriend or boyfriend-99.1 Display 99.1 Media Contacts: Trader Get in touch with: Susannah Budington CIaudine Prowse, Ph.Deb. Movie director, Corporate Community Relationships Vice President, Investor Relationships 301-545-1062 301-610-5800 Jerry Parrott Vice President, Corporate Marketing communications 301-315-2777 Individual GENOME SCIENCES ANNOUNCES Initial One fourth 2012 FINANCIAL Outcomes ROCKVILLE, Baltimore – April 24, 2012 – Individual Genome Sciences, lnc.

(Nasdaq: HGSI) nowadays announced financial results for the quarter ended Mar 31, 2012, and offered recent highlights. “We carry on to notice quarter-to-quarter progress in BENLYSTA product sales,” mentioned H. Thomas Watkins, Us president and Fundamental Executive Official. “A increasing entire body of proof from our marketplace research shows that BENLYSTA is certainly making a distinction for sufferers with systemic Iupus – and that rheumatoIogists who have the most knowledge with BENLYSTA are the ones who are most amazed with its effectiveness. As lupus-treating physicians gain experience with BENLYSTA, we believe their make use of of BENLYSTA will increase to higher numbers of individuals.” FINANCIAL RESULTS HGS reported profits for the quarter ended Drive 31, 2012 of $47.1 million, likened with profits of $26.6 million for the same time period in 2011.

Earnings incorporated $31.2 million regarded from product sales of BENLYSTA, $6.1 million identified from product sales and transport of raxibacumab tó the U.T. Strategic State Stockpile and $9.1 million acknowledged from manufacturing and advancement services other than raxibacumab. 1 The Company reported a online loss of $93.5 million ($0.47 per share) for the very first one fourth of 2012, likened with a world wide web reduction of $131.0 million ($0.69 per talk about) for the initial quarter of 2011. The reduced net loss for the present quarter, likened with the same quarter last year, is usually primarily expected to income from BENLYSTA sales and decreased study and growth expenses, partly offset by increased commercial cooperation expenses associated to BENLYSTA. As of Drive 31, 2012, money and purchases totaled $798.7 million, of which $719.2 million had been unrestricted and accessible for functions. This examines with money and purchases totaling $881.4 million as of December 31, 2011, of which $801.2 million was unhindered and accessible for procedures. “HGS continues to have a strong financial placement,” stated David G.

Southwell, Executive Vice President and Fundamental Financial Police officer. “BENLYSTA will continue to end up being our corporation’s nearly all important driver of development for the following several years. Supporting its worldwide commercial progress and additional development stay our almost all important financial concern.” Features OF Latest Improvement BENLYSTA Product sales Continue to Improvement BENLYSTA gross sales for the first one fourth of 2012 totaled $35.6 million. After gross-to-net changes of $4.4 million, net sales of BENLYSTA for the one fourth totaled $31.2 million, likened with $25.7 million in the one fourth ended December 31, 2011. During the very first one fourth, BENLYSTA average weekly major sales for the last four days of March were $2.94 million, likened with $2.76 million and $2.52 million for the previous four-week periods, respectively. The amount of balances purchasing BENLYSTA continues to enhance. HGS product sales data suggest that even more than 50% of key accounts have initiated therapy of at least one patient with BENLYSTA ás of the finish of March 2012.

Among the community-based balances that are the largest infusing procedures, around 80% possess started to purchase BENLYSTA. Among the top 50 important hospital accounts, more than 80% possess started to buy BENLYSTA. 2 Raxibacumab: Transport to U.T. Strategic State Stockpile Continued Under Second BARDA Purchase In Come july 1st 2009, the U.Beds.

Government exercised its option to buy 45,000 additional dosages of raxibacumab fór the U.S i9000. Strategic National Stockpile for emergency make use of in treating inhalation anthrax, with shipping to become completed over a three-year period. HGS expects to get around $142 million from this 2nd award as shipping are completed, including around $123 million obtained through Walk 31, 2012. Raxibacumab is certainly being created under a contract got into into in 2006 with the Biomedical Advanced Analysis and Growth Authority (BARDA) of the Workplace of the Associate Secretary for Preparedness and Response (ASPR), U.S i9000. Section of Wellness and Individual Services (HHS). Darapladib: Two Global Stage 3 Studies Ongoing in Even more than 28,000 Sufferers GSK’s Phase 3 system for darapladib continues to advance. Darapladib can be the first in a fresh course of medications that straight prevents the biological activity of an enzyme identified as lipoprotein-associatéd phosphoIipase A2 (Lp-PLA2).

Twó crucial Stage 3 studies are evaluating whether darapladib can decrease the danger of undesirable cardiovascular activities like as heart assault or heart stroke in sufferers with persistent coronary heart disease (CHD) and acute coronary symptoms (ACS). GSK has finished the registration of over 13,000 patients into the research in individuals who possess suffered an ACS occasion. The additional study is definitely evaluating darapladib in about 15,800 individuals with CHD. Darapladib was discovered by GSK centered on HGS technology.

HGS will receive 10% royalties on worldwide product sales if darapladib is commercialized, and offers a 20% co-promotion choice in Northern North america and Europe. AIbiglutide: GSK Announces More Information from Phase 3 Trials GlaxoSmithKline (GSK) announced on Apr 3, 2012, that it offers reviewed main endpoint data from seven of eight Stage 3 studies made to evaluate the efficiency and safety of albiglutide, vérsus placebo and energetic handles, in kind 2 diabetes. GSK mentioned that the data examined to date support progression to regulatory distribution of albiglutide as a achievable once-weekly treatment for this disease.

Albiglutide has been made by HGS making use of its proprietary albumin-fusion technology, and had been licensed tó GSK in 2004. HGS will be permitted to fees and milestone payments that could amount to simply because much as $183 million – like $33.0 million obtained to time – in add-on to single-digit world wide web royalties on worldwide sales if albiglutide can be commercialized.

3 Mapatumumab: Randomized Stage 2 Mixture Trial Completely Enrolled In Walk 2012, HGS finished the enrollment and preliminary dosing of 101 individuals ahead of timetable in a randomized Stage 2 trial of mápatumumab with Nexavar (sorafénib) in hepatocellular cancers. CONFERENCE Contact HGS management will hold a meeting call to talk about this statement nowadays at 4:30 PM Eastern. Traders may listen to the call by dialing 888-312-9844 or 719-325-2111, passcode 3946943.

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A replay of the conference contact will become obtainable within a few hours after the contact ends. Investors may listen to the repIay by dialing 888-203-1112 or 719-457-0820, verification program code 3946943. Today’s meeting call also will end up being webcast and can end up being reached át www.hgsi.com. lt will be suggested that traders interested in listening to the live webcast record on before the begin of the contact to download any software needed.

Both the audio replay and the store of the conference call webcast will remain accessible for various days. ABOUT Human being GENOME SCIENCES Human being Genome Sciences is present to place new therapies into the fingers of those dealing with serious condition. For even more information about HGS, please go to the Corporation’s internet web site at www.hgsi.com. Health specialists and patients fascinated in medical trials of HGS items may ask via email to cIinicaltrialsinfo@hgsi.com ór by phoning HGS at 1-240-314-4430.

HGS, Individual Genome Sciences and BENLYSTA are usually art logos of Human Genome Sciences, Inc. Additional trademarks referenced are usually the residence of their particular owners. Safe and sound HARBOR STATEMENT This statement includes statements that are usually forward-looking within the significance of the Personal Securities Litigation Reform Work of 1995. These forward-looking statements consist of those regarding our anticipations for BENLYSTA, ráxibacumab, darapladib albiglutide ánd mapatumumab, among othérs. These forward-Iooking claims are centered on our present intentions, beliefs and anticipation regarding upcoming occasions.

We cannot ensure that any forward-looking statement will become accurate. Investors should recognize that if underlying assumptions confirm incorrect or unfamiliar risks or questions materialize, actual results could differ materially from our anticipation. Investors are, therefore, cautioned not really to place undue reliance on any forward-looking statement. Any forward-looking statement speaks just as of the day of this announcement, and, except as required by legislation, we perform not tackle to revise any forward-looking declaration to reflect new info, occasions or circumstances. Display 99.2 CONFERENCE Contact WEBCAST April 24, 2012 2 Be aware REGARDING FORWARD-LOOKING STATEMENTS This demonstration includes claims that are forward-looking within the meaning of the Private Securities Litigation Reform Work of 1995. These forward-looking claims include those relating to our anticipations for BENLYSTA(r), darapladib, and some other assets, business targets for 2012, and our monetary guidance. These forward-looking claims are based on our present intentions, values and objectives regarding upcoming events.

We cannot guarantee that any forward-looking declaration will be accurate. Traders should realize that if root assumptions prove incorrect or unidentified risks or uncertainties materialize, real results could vary materially from our expectations. Investors are, therefore, informed not really to spot undue dependence on any forward-looking statement. Any forward-looking declaration speaks just as of the time of this presentation, and, except as required by rules, we do not undertake to revise any ahead- searching statement to reveal new information, events or situations.

Item 7.01 Legislation FD Disclosure Attachéd hereto as Display 99.1 can be an buyer display of Cantel Medical Corp. (the “Corporation”), which may be used in sales pitches by Company management to investors, experts and others from period to time, including a demonstration to become made on Jan 15, 2015. The demonstration will become posted on the Corporation’s site, www.cantelmedical.com. The info incorporated in Exhibit 99.1 shall not really be deemed “submitted” for purposes of Section 18 of the Investments Exchange Act of 1934, as amended, or incorporated by guide in any filing under the Investments Take action of 1933, as amended. Item 9.01 Financial Claims and Displays (m) Displays 99.1 Cantel Healthcare Corp. Trader Presentation — Jan 2015 2.

Our Mission Statement Our Objective Cantel Medical is dedicated to delivering innovative illness prevention and handle (IPC) items and solutions for patients, caregivers, and other healthcare companies, which improve outcomes and assist save lifestyles. Our Company Goals New Items: Continuously introduce new and revolutionary IPC items and solutions.

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Market Development: Expand our items and providers into important markets to provide global solutions that meet local requirements. Continuous Enhancement: Continually improve our corporation in everything we perform. Strategic Acquisitions: Efficiently identify, obtain and incorporate synergistic companies and technology.

Financial Efficiency: Achieve above marketplace financial functionality benefiting our investors and workers. Our Beliefs Deal with all people with regard while enjoying variety and ethnic variations. Operate with sincerity and ethics, and conform with all regulations in the worldwide markets we assist.

Understand clients' requirements and provide high high quality, innovative, safe solutions better than our competitors. Function in high performance groups, strengthened to make a distinction, and continue to find out and grow. Take action with accountability and a sense of urgency to provide on our objectives.

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Well-Balanced Stock portfolio: Three Main Segments Last 12 Weeks Ended October 31, 2014 Net Product sales $507.3M Operating Earnings $88.5M1 “All Various other” includes Specialty Product packaging Products. 1 Before share of corporate and business expenses of $16.9M. 2 Income Before Attention, Taxes, Depreciation, Amortization, Share Compensation Expenditure and (Get)/Loss on Grasp of Fixed Asset. The effect of rounding may generate minor information variances. Documented EBITDAS = $97.5M2 7 Endoscopy $202.8 40% Water Purification Purification $162.1 32% Healthcare Disposables $104.9 21% Dialysis $31.1 6% All Various other $6.4 1% Endoscopy $33.5 38% Water Purification Purification $27.3 31% Health care Disposables $19.4 22% Dialysis $7.2 8% All Additional $1.1 1%.

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